Things happen that throw off a schedule, change your days, but we still need to be positive. Grand plans sometimes need to be changed. Not all meetings go according to your vision, treat those as learning experiences.
Ask yourself why? By doing this you are focusing on a solution as opposed to the problem. This also turns a negative into a positive. Turn your NO into the Next Opportunity because it is out there, I promise.
At the end of the day, you are still breathing, your wife will still be there, your kids will still love you, the dog will lick your face, and tomorrow you will awaken with a fresh start.
Practice positive everyday, it will become a part of you. Remember, 366 days of positive, cause negative never takes a day off.